Control of Replication Timing by a Transcriptional Silencer
نویسندگان
چکیده
منابع مشابه
Control of Replication Timing by a Transcriptional Silencer
BACKGROUND Eukaryotic DNA replication starts at many origins. Some origins are used early in S phase, while others are programmed to fire later. In general, late replication is correlated with transcriptional inactivity and with location near the nuclear periphery. However, the mechanisms that determine replication timing are unclear, and the cause-and-effect relationship between late replicati...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2002
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)00871-0